Wu C-Y, Lau BT, Kim H, Sathe A, Grimes SM, Ji HP, Zhang NR* (2021) Integrative single-cell analysis of allele-specific copy number alterations and chromatin accessibility in cancer. Nature Biotechnology, doi: 10.1038/s41587-021-00911-w

Mukherjee S, Agarwal D, Zhang NR & Bhattacharya BB (2020) Distribution-Free Multisample Tests Based on Optimal Matchings with Applications to Single Cell Genomics, Journal of the American Statistical Association.

Rozenblatt-Rosen et al. (2020) The Human Tumor Atlas Network (HTAN): charting tumor transitions across space and time at single-cell resolution. Cell 181, 236. (Consortia paper as part of HTAN)

Zhou Z, Xu B, Minn A, Zhang NR* (2020) Dendro: genetic heterogeneity profiling by single cell RNA sequencing, Genome Biology 21, 10. (R package: DENDRO)

Zhou Z, Ye C, Wang J, Zhang NR* (2020) Surface protein imputation from single cell transcriptomes by deep neural networks, Nature Communications 11, Article number: 651

Agarwal D, Wang J, Zhang NR* (2020) Data denoising and post-denoising corrections in single cell RNA sequencing, Statistical Science 35 (1), 112-128.

Wang X, Park J, Susztak K, Zhang NR, Li M (2019) Bulk Tissue Cell Type Deconvolution with Multi-Subject Single-Cell Expression Reference, Nature Communications 10, 380.

Wang J, Agarwal D, Huang M, Hu G, Zhou Z, Ye C, Zhang NR* (2019) Data denoising with transfer learning in single-cell transcriptomics, Nature Methods 16, 875.

Benci JL et al. (2019) Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade, Cell 178 (4), 933-948. e14.

Nguyen S et al. (2019) Elite control of HIV is associated with distinct functional and transcriptional signatures in lymphoid tissue CD8+ T cells, Science Translational Medicine 11(523).

Agarwal D, Zhang NR* (2019) A rank-based semblance kernel on probability spaces, Science Advances 5 (12), eaau9630.

Huang M, Wang J, Torre E, Dueck H, Shaffer S, Bonasio R, Murray J, Raj A, Li M, Zhang NR* (2018) SAVER: Gene expression recovery for single cell RNA sequencing, Nature Methods 15, 539.

Zhou Z, Wang W, Wang L-S, Zhang NR* (2018) Integrative DNA copy number detection and genotyping from sequencing and array-based platforms, Bioinformatics 34, 2349.

Wang X, Jiang Y, Zhang NR, Small D (2018) Sensitivity analysis and power for instrumental variable studies, Biometrics doi: 10.1111/biom.12873.

Urrutia E, Chen H, Zhou Z, Zhang NR, Jiang Y (2018) Integrative pipeline for profiling DNA copy number and inferring tumor phylogeny, Bioinformatics 34, 2126.

Zhang H, Zhang NR, Li M, Reilly MP (2018) First giant steps towards a cell atlas of atherosclerosis, Circulation Research 122, 1632.

Wang J, Huang M, Torre E, Dueck H, Shaffer S, Murray J, Raj A, Li M, Zhang NR* (2018) Gene expression distribution deconvolution in single cell RNA sequencing, Proceedings of the National Academy of Sciences 115, E6437.

Jiang Y, Nathanson KL, Zhang NR* (2018) CODEX2: full-spectrum copy number variation detection by high-throughput DNA sequencing, Genome Biology 19, 202.

Wang X, Chen H, Zhang NR (2017) DNA copy number profiling using single-cell sequencing, Briefings in Bioinformatics, bbx004, https://doi.org/10.1093/bib/bbx004.

Jiang Y, Zhang NR, Li M (2017) SCALE: modeling allele-specific gene expression by single-cell RNA-sequencing, Genome Biology 18, 74.

Chen H, Jiang Y, Maxwell K, Nathanson K, Zhang NR* (2017) Allele-specific copy number estimation by whole exome sequencing, Annals of Applied Statistics 11, 1169.

Jia C, Hu Y, Kelly D, Kim J, Li M, Zhang NR (2017) Accounting for technical noise in differential expression analysis of single-cell RNA sequencing data, Nucleic Acids Research, 45, 10978.

Maxwell KN, Wubbenhorst B, Wenz BM, Sloover DD, Pluta J, Emery L, Barrett A, Kraya AA, Anastopoulos IN, Yu S, Jiang Y, Chen H, Zhang NR, Hackman N, D’Andrea K, Daber R, Morrissette JJ, Mitra N, Feldman M, Domchek SM, Nathanson KL (2017) BRCA locus-specific loss of heterozygosity in germline BRCA1 and BRCA2 carriers, Nature Communications 8, 319.

Xia LC, Bell JM, Wood-Bouwens C, Chen JJ, Zhang NR, Ji HP (2017) Single molecule-based discovery of complex genomic rearrangements, Nucleic Acids Research 46, e19.

Garman B, Anastopoulos IN, Krepler C, Brafford P, Sproesser K, Jiang Y, Wubbenhorst B, Amaravadi R, Bennett J, Beqiri M, Elder D, Flaherty KT, Frederick DT, Gangadhar TC, Guarino M, Hoon D, Karakousis G, Liu Q, Mitra N, Petrelli NJ, Schuchter L, Shannan B, Sheilds CL, Wargo J, Wenz B, Wilson MA, Xiao M, Xu W, Xu X, Yin X, Zhang NR, Davies MA, Herlyn M, Nathanson KL (2017) Genetic and genomic characterization of 462 melanoma patient-derived xenografts, tumor biopsies and cell lines, Cell Reports 21, 1936.

Wang X, Chen M, Yu X, Pornputtapong N, Chen H, Zhang NR, Powers RS, Krauthammer M (2016) Global copy number profiling of cancer genomes, Bioinformatics, 32, 926.

Zhang NR, Yakir B, Xia LC, Siegmund DO (2016) Scan statistics on Poisson random fields with applications in genomics, Annals of Applied Statistics 10, 726.

Xia LC, Sakshuwong S, Hopmans ES, Bell JM, Grimes SM, Siegmund DO, Ji HP, Zhang NR* (2016) A genome-wide approach for detecting novel insertion-deletion variants of mid-range size, Nucleic Acids Research 44, e126.

Jiang Y, Qiu Y, Minn AJ, Zhang NR* (2016) Assessing intratumor heterogeneity and tracking longitudinal and spatial clonal evolutionary history by next-generation sequencing, Proceedings of the National Academy of Sciences 113, E5528.

Chen H, Bell JM, Zavala NA, Ji HP, Zhang NR* (2015) Allele-specific copy number profiling by next-generation DNA sequencing, Nucleic Acids Research 43, e23.

Jiang Y, Oldridge DA, Diskin SJ, Zhang NR* (2015) CODEX: a normalization and copy number variation detection method for whole exome sequencing, Nucleic Acids Research 43, e39.

Chen H, Zhang NRǂ (2015) Graph-based change-point detection, The Annals of Statistics 43, 139.

Cushing A, Kamali A, Winters M, Hopmans ES, Bell JM, Grimes SM, Li CX, Zhang NR, Moss RB, Holodniy M, Ji H (2015) Emergence of hemagglutinin mutations during the course of influenza infection, Scientific Reports 5, 16178.

Peixoto LL, Wimmer ME, Poplawski SG, Tudor JC, Kenworthy CA, Liu S, Mizuno K, Garcia BA, Zhang NR, Giese K, Abel T (2015) Memory acquisition and retrieval impact different epigenetic processes that regulate gene expression, BMC Genomics 16, S5.

Yue M, Han X, De Masi L, Zhu C, Ma X, Zhang J, Wu R, Schmieder R, Kaushik RS, Fraser GP, Zhao S, McDermott PF, Weill FX, Mainil JG, Arze C, Fricke WF, Edwards RA, Brisson D, Zhang NR, Rankin SC, Schifferli DM (2015) Allelic variation contributes to bacterial host specificity, Nature Communications 6, 8754.

Nadauld LD, Garcia S, Natsoulis G, Bell JM, Miotke L, Hopmans ES, Xu H, Pai RK, Palm C, Regan JF, Chen H, Flaherty P, Ootani A, Zhang NR, Ford JM, Kuo CJ, Ji HP (2014) Metastatic tumor evolution and organoid modeling implicate TGFBR2 as a cancer driver in diffuse gastric cancer, Genome Biology 15,428.

Chen H, Zhang NRǂ (2013) Graph-based tests for two-sample comparisons of categorical data, Statistica Sinica 23, 1479.

Natsoulis G, Zhang NR, Welch K, Bell J, Ji HP (2013) Identification of insertion deletion mutations from deep targeted resequencing, Journal of Data Mining in Genomics and Proteomics 4, 132.

Muralidharan O, Natsoulis G, Bell J, Newburger D, Xu H, Keta I, Ji H, Zhang NR* (2012) A cross-sample statistical model for SNP detection in short-read sequencing data, Nucleic Acids Research 40, e5.

Flaherty P, Natsoulis G, Muralidharan O, Winters M, Buenrostro J, Bell J, Brown S, Holodniy M, Zhang N, Ji HP (2012) Ultrasensitive detection of rare mutations using next-generation targeted resequencing, Nucleic Acids Research 40, e2.

Shen J, Zhang NR* (2012) Change-point model on nonhomogeneous Poisson processes with application in copy number profiling by next-generation DNA sequencing, Annals of Applied Statistics 6, 476.

Muralidharan O, Natsoulis G, Bell J, Ji H, Zhang NR* (2012) Detecting mutations in mixed sample sequencing data using empirical Bayes, Annals of Applied Statistics 6, 1047.

Zhang NR, Siegmund DO (2012) Model selection for high dimensional, multi-sequence change-point problems, Statistica Sinica 22, 1507.

Sun Y, Zhang NR and Owen A (2012) Multiple hypothesis testing, adjusted for latent variables, with an application to the agemap gene expression data, Annals of Applied Statistics 6, 1664.

Chen H, Xing H, Zhang NR* (2011) Estimation of parent specific DNA copy number in tumors using high-density genotyping arrays, PLoS Computational Biology 7, e1001060.

Siegmund DO, Yakir B, Zhang NRǂ (2011) Detecting simultaneous variant intervals in aligned sequences, Annals of Applied Statistics 5, 645.

Efron B and Zhang NRǂ (2011) False discovery rates and copy number variation, Biometrika 98, 251.

Natsoulis G, Bell JM, Xu H, Buenrostro JD, Ordonez H, Grimes S, Newburger D, Jensen M, Zahn JM, Zhang N, Ji HP (2011) A flexible approach for highly multiplexed candidate gene targeted resequencing, PLoS One 6, e21088.

Siegmund DO, Zhang NR, Yakir B (2011) False discovery rate for scanning statistics, Biometrika 98, 979.



For complete list, see Google Scholar.